Endocrine Signaling and Male Reproduction

Epigenetic transgenerational effects of endocrine disruptors on male reproduction.

Endocrine-disrupting chemicals generally function as steroid receptor signaling antagonists or agonists that influence development to promote adult-onset disease. Exposure to the endocrine disruptors during the initiation of male reproductive tract development interferes with the normal hormonal signaling and formation of male reproductive organs. In particular, exposure to the endocrine disrup...

Endocrine Monitoring of Reproduction and Stress

Most wild mammals kept in captivity are managed intensively. Under such conditions, the ability to monitor reproductive status can greatly facilitate attempts to enhance breeding success for many species. More specifi cally, objective and reliable methods for monitoring key reproductive events, such as ovulation and pregnancy, not only fi nd widespread application in the management of natural b...

Testicular Estrogens and Male Reproduction.

Besides somatic cells, aromatase gene expression and its transduction in an active protein in germ cells provides evidence of an additional site for estrogen production within testes of some mammals. Together with the widespread distribution of estrogen receptors in testicular cells, these data illuminate the hormonal regulation of male reproductive function

Physiology of male reproduction.

SYMPOSIUM OVERVIEW Endocrine Modulation of Reproduction

*Reproductive Toxicology Group, National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709; ^Department of Toxicology, Crop Protection Division, Ciba-Geigy, Greensboro, North Carolina; ^Comparative Medicine Clinical Research Center, Departments of Comparative Medicine and Obstetrics & Gynecology, The Bowman Gray School of Medic...